Drugs fail to slow decline in inherited Alzheimer's disease

[Zorro]

Two experimental drugs failed to prevent or slow mental decline in a study of people who are virtually destined to develop Alzheimer’s disease at a relatively young age because they inherited rare gene flaws.

The results announced Monday are another disappointment for the approach that scientists have focused on for years -- trying to remove a harmful protein that builds up in the brains of people with Alzheimer’s, the leading cause of dementia.

“We actually don’t even know yet what the drugs did” in term of removing that protein because those results are still being analyzed, said study leader Dr. Randall Bateman at Washington University in St. Louis, Missouri.

But after five years on average, the main goal of the study was not met — people on either of the drugs scored about the same on thinking and memory tests as others given placebo treatments.

https://www.washingtonpost.com/health/drugs-fail-to-slow-decline-in-inherited-alzheimers-disease/2020/02/10/d112897c-4c01-11ea-967b-e074d302c7d4_story.html

This is disappointing news.

[pandr32]

1. It has been a problem in my family

My sister asked if I was considering being tested for the gene and I told her"no". That was a while ago now. I would rather be looking forward to the future than dreading it. Living one day at a time, too.
Now...to rid ourselves of DT and his merry band of complicit stooges.

[Faux pas]

2. My mom had it and

showed some signs of it by her mid sixties. I'm 70 and so far I'm fine. I'm hoping my marijuana use is helping me not to get it.