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Nevilledog

(51,122 posts)
Mon Jul 20, 2020, 03:49 PM Jul 2020

Oxford Coronavirus Vaccine 'Safe' And Showing 'Promising Results'

https://www.huffpost.com/entry/uk-oxford-coronavirus-vaccine-trial_n_5f15a14fc5b619afc4046655

A UK vaccine against coronavirus has shown “promising” results, findings of the first phases of the study suggest.

The early-stage trial showed the vaccine is “safe, causes few side effects, and induces strong immune responses,” results published in The Lancet said.

However, scientists warned it is still too soon to know if the results are enough, and larger trials are currently under way.

The vaccine, developed by the University of Oxford, is called ChAdOx1 nCoV-19 and is delivered via a chimpanzee virus, called the vaccine vector.

It is made from a genetically engineered virus that causes the common cold in chimpanzees, which is then engineered to express the coronavirus spike protein to trigger a strong immune response in the human body.

The UK government has already ordered 100 million doses of the vaccine.

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Oxford Coronavirus Vaccine 'Safe' And Showing 'Promising Results' (Original Post) Nevilledog Jul 2020 OP
THis is a more traditional vaccine (unlike the mRNA-based Moderna vaccine) hlthe2b Jul 2020 #1
Hey currently I'm all for anything that helps kill this damn virus. Initech Jul 2020 #2
Is this the vaccine whose antibodies disappeared after two months? LonePirate Jul 2020 #3

hlthe2b

(102,292 posts)
1. THis is a more traditional vaccine (unlike the mRNA-based Moderna vaccine)
Mon Jul 20, 2020, 04:03 PM
Jul 2020

Admittedly, I have qualms about the mRNA technology which has NEVER yet resulted in a licensed vaccine and is so specific it could well either miss the mark in stimulating an immune response or produce one insufficiently broad enough to prevent an unwanted non-specific immune reaction upon actual exposure to the virus.

Oxford showing T-cell response at 14 days as well as antibody response. That is encouraging, especially given recent studies showing a rapid diminishment of antibody in natural infection .

LonePirate

(13,426 posts)
3. Is this the vaccine whose antibodies disappeared after two months?
Mon Jul 20, 2020, 04:21 PM
Jul 2020

That’s better than nothing but it still has a long way to go before it will be considered ready for widespread use. A minimum of six months for antibody production is needed (my personal opinion) if this vaccine has any hope of ever leaving the test study.

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