what is the difference between Moderna and Pfizer?

[demtenjeep]

I do not care but was just curious to the differences

[Phoenix61]

1. Phizer has to be kept super cold while Moderna can

be stored in a regular freezer. Johnson can be stored in a regular refrigerator and only requires one dose. It’s not as effective at preventing illness but is extremely effective at preventing hospitalization and death.

[Celerity]

2. Comparing the Covid-19 vaccines developed by Pfizer, Moderna, and Johnson & Johnson

https://www.statnews.com/2021/02/02/comparing-the-covid-19-vaccines-developed-by-pfizer-moderna-and-johnson-johnson/

[Laffy Kat]

3. The main difference I can see is that Moderna vaccine doesn't need to be diluted...

Before administration and it can be kept in a normal freezer. One can be given to teenagers. Here's more:

https://www.astho.org/COVID-19/Pfizer-Moderna-Vaccine-Comparison/

[roamer65]

4. The mRNA in the Moderna vaccine is packaged in a more robust and patented lipid nanoparticle.

That is why it doesn’t need as much refrigeration as the Pfizer vaccine.

[Ms. Toad]

5. Pfizer seems to be slightly more prone to cause anaphalactic reactions;

21/1.8 M v. 10/4+ M

Moderna is slightly more prone to local reactions (itchy red blotch - I haven't seen it reported at all with Pfizer)

Pfizer is 3 weeks between doses; Moderna 4 weeks.

Pfizer was tested for effectiveness a week after the second dose; Moderna at 2 weeks.

Pfizer contains 30 mcg of vaccine; Moderna contains 100 mcg

[LizBeth]

6. 2% effectiveness. I think Pfizer is 98% and Moderna 96%. I say this lightly. There does not seem to

be much pro con for the two. I have been looking for a difference and not seeing it.