J&J: Booster dose of its COVID shot prompts strong response

[SheltieLover]

https://www.localmemphis.com/mobile/article/news/health/coronavirus/vaccine/johnson-johnson-covid-19-booster-shot/507-d09de0c5-3952-462a-8e16-b8db1e2154cc

WASHINGTON — Johnson & Johnson announced on Tuesday that receiving a booster shot of its coronavirus vaccine can provide stronger protection from the virus.

In a Phase 3 study, the company said that the second shot of its vaccine received 56 days after the first provided 94% protection against COVID-19 in the United States. It added that it offers full protection against severe/critical cases of COVID-19 at least 14 days post-final vaccination.

J&J said in a statement that it ran two early studies in people previously given its vaccine and found that a second dose produced an increased antibody response in adults from age 18 to 55. The study's results haven't yet been peer-reviewed.

The New Jersey-based company added that when a booster shot was given after two months, "antibody levels rose to four to six times higher than observed after the single shot."

More at link.

[Hugin]

1. KnR this one, too. n/t

[SheltieLover]

2. Thx!

Great news!

[hibbing]

3. It's been way past 56 days

Not sure what I'm supposed to do, I got the J & J way back in March I think it was. Does this mean I'll eventually need two more J & J shots or should I earn my Facebook medical degree and start shopping for livestock medication?


Peace

[NoMoreRepugs]

4. TY for the morning chuckle.

[GPV]

5. Same here!

[CanyaDigIt]

6. From CNN article

https://www.cnn.com/2021/09/21/health/johnson-vaccine-two-doses-booster/index.html


"A second study showed people given a booster shot six months or longer after their first dose had a 12-fold increase in antibodies -- compared to a four-fold increase for people who got a second dose at two months. "

"For outstanding protection, then a second shot can be given at any time between two months and eight months -- and the longer you wait, the better."

[DenaliDemocrat]

7. If you look at the meta data, J&J did not reach

Full protection until out past day 100. It works differently than the mRNA. It also showed better t-cell and b-cell levels.

[wnylib]

15. If J&J shows better T and B cell levels,

would it be beneficial for people who got mRNA shots to get a J&J booster?

[DenaliDemocrat]

22. No one really knows for certain BUT

In Europe people who mixed Astra Zeneca with an nRNA saw crazy antibody titers. So likely?

I am a biochemist and IF I can, I currently plan on getting J&J as my booster. Obviously that could change as data is collected

[underpants]

8. Kicking.

Good to finally get some sort of an update.

[themaguffin]

9. woohoo

[Auggie]

10. Has the FDA approved this booster yet?

[SheltieLover]

11. Not that I know of.

Sorry.

[Auggie]

19. My Doc is in a dilemma and sent out this question to J&J recipients a few weeks back:

Are we in favor of getting the J&J booster without FDA approval?

Sounds like he wanted to offer boosters but would feel better if the government approves. He was willing to go with the practice majority if it said yes.

Good Doc, you know?

[SheltieLover]

20. I'd grab it, personally!

You are lucky to have a doc with bling between their neudons!

Ty for sharing!

[ZonkerHarris]

12. sounds like it should have been a 2 shot process like Moderna etc in the 1st place

but they wanted to be the only one shot out there.

[wnylib]

16. Maybe the mRNA shots should

have been triple shots from the start.

We are learning as we go along.

[ZonkerHarris]

17. I'm good with an annual shot like for the flu. or boosters. whatever works.

[wnylib]

18. Same here.

[SheltieLover]

21. Same here

[appalachiablue]

13. Good J&J info. Want to X-post it to 'Health'? (I'm Moderna)

ALSO:

WSJ, Sept. 21, 2021.

- J&J Says Covid-19 Vaccine Booster Two Months After First Shot Increases Protection -

Johnson & Johnson said a booster dose of its Covid-19 vaccine administered two months after the first shot increased protection against symptomatic illness in trial participants, as federal regulators evaluate data for the country’s strategy for rolling out boosters.

Data released Tuesday from a late-stage clinical trial showed that study participants in 10 countries including the U.S. who received a second dose of the company’s vaccine two months after the first had 75% protection against symptomatic Covid-19. Participants in the U.S. had 94% protection against the illness. J&J didn’t explain the reason for the difference in efficacy rates.

A double dose of the vaccine provided participants with 100% protection against severe or critical Covid-19 at least two weeks after the second shot, J&J said. The company earlier this year said a large clinical trial showed that a single dose of its vaccine was 66% effective at protecting people from moderate to severe Covid-19. “We now have generated evidence that a booster shot further increases protection against Covid-19 and is expected to extend the duration of protection significantly,” said Paul Stoffels, chief scientific officer at J&J. The company said it has shared available data with the FDA.

..The Biden administration is hoping to begin at least part of its boosting strategy this week. It is waiting for the FDA to authorize additional doses of the vaccine from Pfizer Inc. and BioNTech SE for people who are 65 years old and over or at high risk of developing severe Covid-19. A Centers for Disease Control and Prevention advisory panel is set to discuss the Pfizer boosting strategy on Wednesday and Thursday. Plans to offer boosters more widely were scaled back as federal health officials and medical experts remain divided over the need for boosters and regulators have asked for more time to review data from J&J and Moderna Inc...

https://www.msn.com/en-us/health/medical/j-j-says-covid-19-vaccine-booster-two-months-after-first-shot-increases-protection/ar-AAOF6Da

[elleng]

14. Good