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madokie

(51,076 posts)
Tue Dec 2, 2014, 02:25 AM Dec 2014

Are We Big Pharma's Guinea Pigs? 8 Drugs Used by Millions Before Being Pulled for Dangerous Side-Ef

Big Pharma hopes we'll forget about these drugs.


Blockbuster drugs like Viagra, Lipitor, Prozac and Nexium have made Big Pharma one of the nation's top industries. Even before direct-to-consumer advertising on TV, there were blockbuster drugs like Ritalin, Valium, Tagamet and Premarin. To be a blockbuster a drug has to 1) be usable by almost everyone; 2) be used every day; 3) be used indefinitely; 4) solve an everyday health problem like heartburn or high cholesterol; 5) have a fun or memorable ad campaign; 6) get social buzz; and 7) be sold to a large number of people quickly.

The last qualification—quick sales to millions—is crucial because Big Pharma has a small sales window before a patent runs out. But it's also dangerous because many risks don't emerge until millions take the drug so the public serves as unwitting guinea pigs. In fact, the "early user/guinea pig" factor is what sunk Vioxx 10 years ago.

Because of patent pressure, minor drug risks are often only admitted when the patent runs out, a ruse AlterNet has written about. But when risks can't be ignored, even if the drug is selling briskly, the drug will be unceremoniously withdrawn and seldom mentioned again. Here are some blockbusters in the drug graveyard that Big Pharma hopes we will forget about.

1. Darvon and Darvocet

Is an opioid-linked medication that relieves pain worth the overdoses, death, addiction and abuse that are often in its wake? It is a question we hear today with drugs like OxyContin, but dates all the way back to 1957 when Eli Lilly began marketing Darvon.


http://www.alternet.org/drugs/are-we-big-pharmas-guinea-pigs-8-drugs-used-millions-being-pulled-dangerous-side-effects?paging=off¤t_page=1#bookmark
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Are We Big Pharma's Guinea Pigs? 8 Drugs Used by Millions Before Being Pulled for Dangerous Side-Ef (Original Post) madokie Dec 2014 OP
I remember a huge expose in some newspaper (WSJ?) years ago Blue_Tires Dec 2014 #1
Thanks for this report... ReRe Dec 2014 #2
good for you, but the point is Big Pharma's take-down of the American people, ellenrr Dec 2014 #6
I'm sorry... ReRe Dec 2014 #7
Bookmarked, but isn't this obvious? bvf Dec 2014 #3
I took a fair amt of Darvon and Darvocette littlewolf Dec 2014 #4
As if there's any doubt IkeRepublican Dec 2014 #5
Message auto-removed Name removed Dec 2014 #8
Free trade! We are no different than any other natural resource to the profit machine. tk2kewl Dec 2014 #9

Blue_Tires

(55,445 posts)
1. I remember a huge expose in some newspaper (WSJ?) years ago
Tue Dec 2, 2014, 03:15 AM
Dec 2014

about how regulatory teeth and testing standards had been loosened at the FDA (mostly through Big Pharm lobbying $$$$), allowing a lot of barely-tested meds out in the marketplace (with the inevitable consequences)...This was the time when antidepressants, anti-cholesterol, etc were really big business and everyone was rushing their products to market -- Like maybe 1999 or 2000, so I'm damn sure things have only trended downward since that story...

ellenrr

(3,864 posts)
6. good for you, but the point is Big Pharma's take-down of the American people,
Tue Dec 2, 2014, 05:53 AM
Dec 2014

not your individual health. I mean - I do wish you good health, but that is not the point here.

 

bvf

(6,604 posts)
3. Bookmarked, but isn't this obvious?
Tue Dec 2, 2014, 04:48 AM
Dec 2014

You only have to see a pharmaceutical ad or two on TV that claims in ten words that a particular product will help this or that problem, and then goes on to use fifty more warning you of all the possible complications.

Yay capitalism.

IkeRepublican

(406 posts)
5. As if there's any doubt
Tue Dec 2, 2014, 05:15 AM
Dec 2014

Shit yeah, we are.

Big Pharm Co's keep aside a ton of dough when the results come in (people get sick from it or worse).

Response to madokie (Original post)

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