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Bosonic

(3,746 posts)
Tue Feb 3, 2015, 12:25 PM Feb 2015

UK House of Commons OKs making babies from DNA of 3 people

Source: AP

LONDON (AP) -- British lawmakers in the House of Commons voted Tuesday to allow scientists to create babies from the DNA of three people - a move that could prevent some children from inheriting potentially fatal diseases from their mothers.

The vote in the House of Commons was 382-128 in favor. The bill must next be approved by the House of Lords before becoming law. If so, it would make Britain the first country in the world to allow embryos to be genetically modified.

The controversial techniques - which aim to prevent mothers from passing on inherited diseases - involve altering a human egg or embryo before transferring it into the mother. British law currently forbids any such modification and critics say approving the techniques could lead to the creation of "designer babies."

Defects in the mitochondria can result in diseases including muscular dystrophy, heart, kidney and liver failure and severe muscle weakness.

Read more: http://hosted.ap.org/dynamic/stories/E/EU_MED_BRITAIN_3_PERSON_BABIES?SITE=AP&SECTION=HOME&TEMPLATE=DEFAULT

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UK House of Commons OKs making babies from DNA of 3 people (Original Post) Bosonic Feb 2015 OP
If it's a boy, let's name him Three Pete. Schema Thing Feb 2015 #1
This is fucking stupid...you scared your baby will come out jacked up...ADOPT A KID snooper2 Feb 2015 #2
+1 Nihil Feb 2015 #6
A Mother has allele pairs that she inherited from her father and her mother. DhhD Feb 2015 #3
Mitochondrial DNA is entirely separate from nuclear DNA muriel_volestrangler Feb 2015 #4
Everyone fine with ‘designer babies’ if it means they don’t do shits T_i_B Feb 2015 #5

DhhD

(4,695 posts)
3. A Mother has allele pairs that she inherited from her father and her mother.
Tue Feb 3, 2015, 01:50 PM
Feb 2015

Using the mitochondria of genes of the Mother's father, he could supply to his grandchild, the better genes of the family (or even the great uncle would have the same mitochondrial DNA as the Mother's father). In my opinion, this line of session would be the most ethical. There is the epi-genome in which the genes of the grandparents are remembered by the grandchild that occurs naturally, like in diabetes. Perhaps the genes from the epi-genome can someday replace mutated genotypes or lethal genes.

Perhaps the human gene for producing Vitamin C could be repaired. Vitamin C helps keep nitrites from forming in the stomach from processed food proteins.

muriel_volestrangler

(101,345 posts)
4. Mitochondrial DNA is entirely separate from nuclear DNA
Tue Feb 3, 2015, 03:28 PM
Feb 2015

and comes only through the female line, so there is no more relation of the mother's father's mtDNA to the baby than for, say, the baby's father's mtDNA. In theory, everyone ought to have identical mtDNA, if it were not for copying mistakes when mitochondria divide. If the mistakes don't affect the way the mitochondria function, then they just provide a way of tracing ancestry; if the mutation causes a problem (eg by changing a protein significantly), you can get these inherited diseases.

What this procedure will do is get well-functioning mtDNA from another egg. This has nothing at all to do with the epigenome.

T_i_B

(14,741 posts)
5. Everyone fine with ‘designer babies’ if it means they don’t do shits
Wed Feb 4, 2015, 08:26 AM
Feb 2015
http://www.thedailymash.co.uk/news/science-technology/everyone-fine-with-designer-babies-if-it-means-they-dont-do-shits-2015020495031

THE public has expressed total approval for genetically altered babies that do not need to shit.

Scientists admitted they already had made a prototype shitless baby called Robbie who expels waste matter in the form of odourless pods, which instead of coming out of his arse are removed via a hatch in his back.

Geneticist Mary Fish said: “Robbie is a normal, healthy child except nothing comes out of his backside. A couple of times a day you have to check his back for waste-pods which smell slightly of lavender and have a marble-like sheen which means they make appealing ornaments.
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