German Scientists Say Figured Out Why AstraZeneca & J&J COVID Vaccines Can Cause Rare Blood Clots
- 'German scientists say they've figured out why AstraZeneca & Johnson & Johnson COVID-19 vaccines can cause rare blood clots,' Business Insider, by Catherine Schuster- Bruce, May 28, 2021. - Ed.
- They say the vaccines can cause "mutant" proteins to escape cells, triggering a response - The hypothesis hasn't been proved or scrutinized by experts, and other theories exist.
German scientists say they've figured out why some COVID-19 vaccines can cause unusual blood clots in rare cases. The team of scientists from Goethe University in Frankfurt, Germany said Wednesday that the delivery mechanism for AstraZeneca and Johnson & Johnson's vaccines was responsible for causing blood clots after immunization. All four COVID-19 vaccines widely used in the West work by delivering a piece of genetic code into the body.
This teaches the body to create a harmless part of the virus, which triggers an immune response.
The body can then stage the same response if it later detects the real virus.
Vaccines that use mRNA technology, including Pfizer's and Moderna's, deliver the genetic material to the fluid part of the cell. Adenovirus-based vaccines, such as J&J's and AstraZeneca's, deliver it to the central part of the cell, called the nucleus, the scientists said in a study, which hasn't been scrutinized by other experts in a peer review. According to the scientists, this is where the issue lies. While the harmless part of the virus is being made in the nucleus, bits of genetic material can break off, creating "mutant" proteins that leave the cell and travel around the body. Blood vessel walls respond to these proteins, which triggers blood clots, they said.
Unusual blood clots, particularly in the brain, are a very rare side effect of both vaccines, according to regulators. For AstraZeneca's vaccine, 86 cases of unusual blood clots were reported out of 25 million people who had received the shot as of March 22, according to the European Medicines Agency. For J&J's vaccine, there were eight reports of serious blood clots as of April 13, when more than 7 million people had received the shot, according to the EMA.
> Young women have had the clots more often than other groups. The scientists suggested that older people are less likely to get the clots partly because their immune responses are weaker. They added that women naturally have stronger immune responses than men.
The German scientists' hypothesis hasn't been proved...
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https://www.businessinsider.com/vaccine-astrazeneca-johnson-johnson-blood-clots-side-effects-covid-2021-5
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