Israeli Trial, World's First, Finds 4th Dose 'Not Good Enough' Against Omicron
- Times of Israel, Jan. 17, 2022. - Ed. - Expert at Sheba Medical Center says jab raises COVID antibody levels, but there are ‘still a lot of infections’ among those who received it. -
Nearly a month after Sheba Medical Center launched a landmark study to test the efficacy of a 4th COVID shot, the hospital said Monday that this 4th booster was only partially effective in protecting against the Omicron strain. “The vaccine, which was very effective against the previous strains, is less effective against the Omicron strain,” Prof. Gili Regev-Yochay, a lead researcher in the experiment said. “We see an increase in antibodies, higher than after the 3rd dose.” “However, we see many infected with Omicron who received the 4th dose. Granted, a bit less than in the control group, but still a lot of infections,” she added.
“The bottom line is that the vaccine is excellent against the Alpha and Delta [variants], for Omicron it’s not good enough,” she said.
Regev-Yochay added that it is still probably a good idea to give a 4th shot to those at higher risk, but intimated that perhaps the current campaign, which also offers the jab to the over-60s, should be amended to only include even older groups. She did not elaborate. The hospital did not release more specific data. Regev-Yochay said the results of the research are only preliminary, but indicated that she was providing the initial information since there was high public interest in the matter.
Hours after releasing the results, Sheba published a statement calling for “continuing the vaccination drive for risk groups at this time, even though the vaccine doesn’t provide optimal protection against getting infected with the variant.” Hebrew media reported that the hospital was pressured into issuing that statement after the Health Ministry didn’t like the publication of the study’s initial results. Prime Minister Naftali Bennett has pushed ahead with expanding Israel’s 4th dose program, despite the lack of data.
As of Sunday night, over 500,000 Israelis have been inoculated with a 4th dose. The Health Ministry began offering 4th vaccine shots to Israelis 60 and older, the immunocompromised, and medical workers last month. Sheba’s trial program, which began in December with 150 medical staff being given the shot, is many times smaller than normal drug trials, which usually involve thousands of volunteers who results are tracked for months. But it is also the only known study of the effects of a 4th dose.
Israel is pinning hopes that the extra booster may help keep the Omicron variant from overwhelming hospitals and shutting down normal life...
https://www.timesofisrael.com/israeli-trial-worlds-first-finds-4th-dose-not-good-enough-against-omicron/
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