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Particulate matter from modern gasoline engines damages our lungs
http://www.alphagalileo.org/ViewItem.aspx?ItemId=154155&CultureCode=en[font face=Serif][font size=5]Particulate matter from modern gasoline engines damages our lungs[/font]
27 June 2015 Bern, University of
Under embargo until 29 June 2015 09:00 GMT
[font size=3]Particulate matter from gasoline engines is harmful to our airways, regardless of whether the engines are a bit older or comply with recent EU standards. Fine dust particles allow pathogens to enter the lungs easier. Researchers at the University of Bern and the Paul Scherrer Institute PSI have shown this conducting a realistic laboratory experiment.
…
A newly developed aerosol deposition chamber also allowed for the particles to be realistically deposited on cell cultures from healthy and diseased airways. “As a result we were able to clarify the risk for particularly sensitive groups of people, who never would have been able to take part in a study for ethical reasons,” says Josef Dommen.
The deposited particle mass from 10 to 350 nanograms (a billionth of a gram) per square centimeter of cell surface corresponds to an airway daily dose of slightly polluted, rural air with 20 micrograms (a millionth of a gram) PM per cubic meter of air through to very high air pollution in a megacity (1000 micrograms PM per cubic meter of air).
The results showed: cell death increased in relation to the particle dose with all cell cultures. In addition, less inflammatory mediators, which are extremely important for our body’s immune system, were released by the cells, also in relation to the dose. “Both reactions reduce the airway cells’ ability to react appropriately to a subsequent viral or bacterial attack,” explains Marianne Geiser. This cell damage was also observed for the smallest particle dose used, which indicates that there is no threshold.
…[/font][/font]
27 June 2015 Bern, University of
Under embargo until 29 June 2015 09:00 GMT
[font size=3]Particulate matter from gasoline engines is harmful to our airways, regardless of whether the engines are a bit older or comply with recent EU standards. Fine dust particles allow pathogens to enter the lungs easier. Researchers at the University of Bern and the Paul Scherrer Institute PSI have shown this conducting a realistic laboratory experiment.
…
A newly developed aerosol deposition chamber also allowed for the particles to be realistically deposited on cell cultures from healthy and diseased airways. “As a result we were able to clarify the risk for particularly sensitive groups of people, who never would have been able to take part in a study for ethical reasons,” says Josef Dommen.
The deposited particle mass from 10 to 350 nanograms (a billionth of a gram) per square centimeter of cell surface corresponds to an airway daily dose of slightly polluted, rural air with 20 micrograms (a millionth of a gram) PM per cubic meter of air through to very high air pollution in a megacity (1000 micrograms PM per cubic meter of air).
The results showed: cell death increased in relation to the particle dose with all cell cultures. In addition, less inflammatory mediators, which are extremely important for our body’s immune system, were released by the cells, also in relation to the dose. “Both reactions reduce the airway cells’ ability to react appropriately to a subsequent viral or bacterial attack,” explains Marianne Geiser. This cell damage was also observed for the smallest particle dose used, which indicates that there is no threshold.
…[/font][/font]
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