The logic of vaccine mix n' match
Last week, the U.S. Food and Drug Administration and the Disease Control and Prevention authorized and recommended boosters of both the Moderna and Johnson & Johnson (J&J) COVID-19 vaccines. Moderna’s booster comes in just a half dose, and is recommended for people over 65, people over 50 with certain conditions, and people who work in high-exposure jobs. For J&J vaccine recipients, boosters were recommended for everyone over 18.
Though the CDC recommended that people boost with the vaccine they started with, they also endorsed a “mix n’ match” approach. This is particularly salient for Americans who received the J&J vaccine, considering its laggard performance in preventing breakthrough delta infections relative to its mRNA cousins.
Indeed, a recent National Institutes of Health study found that among people whose first vaccination was with J&J, receiving a second J&J dose led to a four-fold increase in antibody reactivity in a test tube. But boosting with Pfizer led to a 35-fold increase — and boosting with Moderna led to a 76-fold increase.
https://www.metrotimes.com/detroit/the-logic-of-vaccine-mix-and-match/Content?
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No data on booster after 2 Moderna vacs.
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