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xchrom

(108,903 posts)
Tue Sep 11, 2012, 08:12 AM Sep 2012

Anti-inflammatories tied to cardiac risk

http://www.sciencenews.org/view/generic/id/344785/title/Anti-inflammatories_tied_to_cardiac_risk_

People who have survived a heart attack seem to increase their risk of having another one, or of dying, by taking common painkillers called NSAIDs, a popular class of drugs that includes ibuprofen.

The unsettling link between non-steroidal anti-inflammatory drugs and heart attack risk is not new. The American Heart Association released guidelines in 2007 discouraging the use of any NSAIDs among people with a history of cardiovascular disease. Researchers in Denmark now bolster that link with the largest study to date of NSAID use in heart patients. The findings appear September 10 in Circulation.

In conducting the analysis, the scientists mined a huge database to identify every first-time heart attack in people 30 years old or older that occurred in the country between 1997 and 2009, nearly 100,000 people in all. The researchers then cross-checked this information with death records, subsequent heart attacks and NSAID prescriptions. (Most NSAIDs in Denmark are prescribed.) About 44 percent of people were prescribed an NSAID during the five years following a first heart attack.

Compared with people who didn’t get NSAIDs via prescription, those who did were 63 percent more likely to die over the next five years and 41 percent more likely to die specifically of a heart problem or to have another heart attack.
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madrchsod

(58,162 posts)
2. aspirin is a blood thinner that helps prevent strokes
Tue Sep 11, 2012, 08:21 AM
Sep 2012

i have to take at least 250mg a day with my other heart medicine.

HereSince1628

(36,063 posts)
3. Technically aspirin is an NSAID, but it has anti-clotting properties...
Tue Sep 11, 2012, 08:27 AM
Sep 2012

other nsaids don't have.

After my by-pass surgery (which wasn't preceded by a heart attack) I was told to do the daily baby aspirin thing. At that time I was told that the other nsaids don't provide protection as aspirin did.

Too bad about the other nsaids, because 800 mg Ibuprofin was really helpful when I had a combination rotator cuff and biceps-tendon injury.

eppur_se_muova

(36,269 posts)
7. NS is "non-steroidal", so that's lumping a lot of different medicines together.
Tue Sep 11, 2012, 12:08 PM
Sep 2012

Best not to define categories by exclusion.

woodsprite

(11,916 posts)
4. I can't take Ibuprofin or similar anti-inflamatories
Tue Sep 11, 2012, 09:05 AM
Sep 2012

They shoot my BP way up. I started taking some Voltaran (sp?) for arthritis in my knees and had real success with it. When I went to my onco for a checkup, he checked my BP. Didn't seem worried, but told me it was 185/100 and he thought I should come off the the script. He told me to take Arthritis-strength Tylenol. The same thing happens to me with decongestants (the old Sudafed). I'm very careful now when I take anything, If I really need something, I try to make it CoricidanHBP or the Tylenol/acetominiphan that I can find.

I'm rationing them now because they're almost impossible to find. Any Tylenol product seems to be.

My son's doc told me to give him Tylenol Jr if he gets a headache. The brand name seems to work well for him and he doesn't mind taking it, we don't use it that often, so I do look for it. I ended up getting a Walgreen's substitute last time because I couldn't find any Tylenol on the shelf.

Seems something funky is going on with them. I know they've had a lot of recalls, but I thought they were big enough to overcome that. The pharmacist says Benedryl is the same way.

kickysnana

(3,908 posts)
6. NSAIDS treat pain...
Tue Sep 11, 2012, 11:59 AM
Sep 2012

people with cardio-disease often are in pain. Pain is a good symptom something is wrong. it also shortens life all by itself.

I don't know anybody who takes ibuprofen if they don't have enough pain to need it.

This study has identified a problem but have not sorted through the cause and effect in any meaningful way.

hedgehog

(36,286 posts)
8. That was my reaction _ people taking anti-inflammatories are treating inflammation -
Wed Sep 12, 2012, 10:53 AM
Sep 2012

and isn't inflammation itself tied to cardio vascular disease? It's be ironic if we discover that the real problem is that their dosage of NSAIDS is too low!

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