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Turning Up Gene Expression to Treat Disease
Turning Up Gene Expression to Treat Disease / Cell, December 14, 2017 (Vol. 171, Issue 7)
Uploaded on Dec 4, 2017
In a new study, the therapeutic potential of Cas9-based epigenetic gene activation is explored in mouse models of type I diabetes, acute kidney injury, and muscular dystrophy.
Check out the paper at: http://www.cell.com/cell/fulltext/S00....
H.-K. Liao, F. Hatanaka, T. Araoka, P. Reddy, M.-Z. Wu, Y. Sui, T. Yamauchi, M. Sakurai, D. O'Keefe, E. Nunez, et al. (2017). In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation. Cell 171.
And read more great research at http://www.cell.com/cell/home.
Uploaded on Dec 4, 2017
In a new study, the therapeutic potential of Cas9-based epigenetic gene activation is explored in mouse models of type I diabetes, acute kidney injury, and muscular dystrophy.
Check out the paper at: http://www.cell.com/cell/fulltext/S00....
H.-K. Liao, F. Hatanaka, T. Araoka, P. Reddy, M.-Z. Wu, Y. Sui, T. Yamauchi, M. Sakurai, D. O'Keefe, E. Nunez, et al. (2017). In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation. Cell 171.
And read more great research at http://www.cell.com/cell/home.