littlemissmartypants
littlemissmartypants's JournalHe's a psychopath.
Thanks for this. ❤ What the Immune System Does Between the First and Second Dose
From the article. . .
WHY MRNA VACCINES NEED TWO DOSES TO BEST WORK AND WHAT DELAYS MIGHT MEAN
Sub Header:
What the Immune System Does Between the First and Second Dose:
The biology through which the mRNA vaccines induce their protection from COVID-19 is fundamentally different from that with other vaccines.
Pfizer and Moderna vaccines use messenger RNA that encodes the spike glycoprotein. Upon injection of the vaccine, the mRNA enters into immune cells called dendritic cells. The dendritic cells use the instructions written in the mRNA to synthesize the hallmark spike glycoprotein, which characterizes the SARS-CoV-2 virus that causes COVID-19. These immune cells then show the spike glycoprotein to B-cells, which then make anti-spike antibodies.
Dendritic cells recognize viruses and present information about the spike protein to T-cells. T-cells provide information about the viral spike protein to B-cells, which are transformed to memory B-cells that store information about the virus. When this memory B-cell is activated with an infection or the second dose of the vaccine, this causes some of the B-cells to change into plasma B-cells that secrete protective antibodies that fight the virus.
The mRNA vaccines are uniquely capable of inducing a special kind of immune cell called a T-follicular helper cell to help B-cells produce antibodies. The T-cells do this through direct contact with the B-cells and by sending chemical signals that tell the B-cells to produce antibodies. It is this help in antibody production that makes these vaccines so effective.
More...
https://news.virginia.edu/content/why-mrna-vaccines-need-two-doses-best-work-and-what-delays-might-mean
I had my first Moderna. I was sick for four days with fatigue, nausea, muscle and join pain with a sore arm, shoulder. I'd do it again a hundred times if I could help my family, friends and neighbors fight getting Covid.
(I was also brought up in a family that believes it is rude to talk about one's medical issues in so called "polite company" but here we are...)
Thanks for sharing the article, dalton99a.
❤
Local NAACP chapter calls for Pasquotank Co. Sheriff's resignation, sheriff's office ask for ...
Local NAACP chapter calls for Pasquotank Co. Sheriffs resignation, sheriffs office ask for internal investigation
WAVY Web Staff and Jon Dowding
3 hours ago
ELIZABETH CITY, N.C. (WAVY) The family of Andrew Brown Jr. along with Rev. Dr. William J. Barber II held a press briefing Saturday afternoon in Elizabeth City.
Rev. Barber is the president and senior lecturer of Repairers of the Breach and co-chair of the Poor Peoples Campaign: A National Call for Moral Revival.
Browns family was joined by civil rights attorney Harry Daniels and Pasquotank County NAACP chapter president Keith Rivers.
42-year-old Andrew Brown Jr. was shot and killed by law enforcement during the execution of a search warrant Wednesday in Elizabeth City.
More at the link.
https://www.wavy.com/news/north-carolina/family-of-andrew-brown-jr-holds-press-briefing-in-elizabeth-city/
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Millions of dollars of unsold Girl Scouts cookies stacked up in metro Atlanta warehouse
https://www.wsbtv.com/news/local/north-fulton-county/millions-dollars-unsold-girl-scouts-cookies-stacked-up-metro-atlanta-warehouse/GSY2UBRCZZBPVACAYK4432U3WA/April 23, 2021 at 9:44 p.m. UTC
By Berndt Petersen
ALPHARETTA, Ga. Metro Atlanta Girl Scouts are sitting on nearly $3 million worth of cookies that they cannot sell because of the COVID-19 pandemic.
Snip
Top cookie seller Najya Robinson told Channel 2′s Berndt Petersen that she cannot believe how high the cases are stacked.
Its a lot of cookies! I did not know there was this many cookies left over, she said.
Snip
Before the pandemic, local troops would sell four million boxes, but even with the cookie drive being extending through April, only two and a half million boxes have been sold.
Snip
The cookies do not expire until September and will keep longer if frozen, but the inside of a warehouse can get hot during the summer.
Robinson says she has already sold 500 boxes of cookies and will keep pushing.
Snip...
Short article, videos at the link.
You can purchase cookies from the Georgia Girl Scouts at Showmethecookies.com
https://www.girlscoutsatl.org/en/productprogram/girl-scout-cookie-program.html?ref=com
And from the Girl Scout website at
https://www.girlscouts.org/en/cookies/all-about-cookies/How-to-Buy.html
❤ (former Girl Scout) pants
There Will Be 2 Types of Post-pandemic Socializers
One group will say yes as often as it can. The other wont be able to forget how nice it is to sit at home on the couch.
JOE PINSKER
10:37 AM ET
A post-pandemic discussion question: You get home from work on a Friday night and change into sweatpants. Its been an exhausting week. A text message comes in. Your good friend wants to know if youd like to meet up last minute for a drink, which is something thats safe to do again. Youd love to catch up, but youre pretty tired. Do you go?
Snip
On the one hand, people will be freshly aware that they shouldnt take the ability to attend social gatherings for granted. On the other, they also will have experienced, albeit involuntarily, the occasional pleasures of having fewer social commitments. Introverts and extroverts alike may feel torn between taking advantage of their regained freedom and preserving some of the quiet of pandemic life, but many people will end up in one of two distinct camps.
The first is one we can call Team Yes. Post-pandemic, I dont intend to wait if I want to try a restaurant or go to an event, Ilona Westfall, a 38-year-old freelance writer in Lakewood, Ohio, told me. I plan on saying yes more. Yes to parties, yes to concerts, yes to beach hangouts with my friends.
After more than a year of not having much to say yes to, it would be hard not to feel that sort of urgency. But nationwide, this reaction will likely be tempered by a newfound taste for a lower-key life. Per a report
https://theharrispoll.com/the-great-awakening/
released by the Harris Poll in March, three-quarters of survey respondents said they learned during the pandemic that they preferred smaller social gatherings at home or at [a] friends place over going out to bars or restaurants. A similar proportion predicted that in the post-pandemic world, they would miss the comfort of [their] home while socializing.
Snip
More at the link.
https://www.theatlantic.com/family/archive/2021/04/post-pandemic-socializers-two-types/618678/
❤ pants
The January 6th VICE Video, if you haven't seen it, you should
Total RunTime Run time: 45:39
This a compilation of citizen journalists, published videos and video captures that have been joined in chronological order for a comprehensive video diary of the events at the Capitol on January 6th, 2021.
It will be difficult to do, but watch until the end.
The drumming BBC Weatherman, cross post from Musicians
Drumming weatherman... the sequel. LIVE 🥁 😆 this was so much fun! https://t.co/qPYXt4NTf3
https://twitter.com/OwainWynEvans/status/1382764764334526472
Drumming weatherman... the sequel. LIVE 🥁 😆 this was so much fun! https://t.co/qPYXt4NTf3
As a drummer I can say that this is epic.
Look how happy he is, totally infectious. In a good way.
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Evergiven Update
This is a timelapse video simulation of the successful refloating operation of the stranded container ship Ever Given that blocked the Suez Canal.
The video is based on real-time ship position data, reconstructed by the team of VesselFinder.
https://www.vesselfinder.com/
(Apr 1, 2021) The Suez Canal Authority launched an investigation into the giant cargo ship Ever Givens grounding.
https://www.vesselfinder.com/news/20530-The-Suez-Canal-Authority-launched-an-investigation-into-the-giant-cargo-ship-Ever-Givens-grounding
Her current location:
https://www.vesselfinder.com/?imo=9811000
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American Masters, Oliver Sacks: His Own Life
American Masters, Oliver Sacks: His Own Lifehttps://www.thirteen.org/programs/american-masters/oliver-sacks-his-own-life-audio-descriptive-version-fa4fvl/
Oliver Sacks: His Own Life (Audio Descriptive Version*)
Explore the life and work of the legendary neurologist and storyteller, as he shares intimate details of his battles with drug addiction, homophobia, and a medical establishment that accepted his work only decades after the fact.
And here: https://www.thirteen.org/programs/american-masters/oliver-sacks-his-own-life-qdlync/
Total run time: 1:49:28
AIRED: 4/9/2021
EXPIRES: 5/8/2021
*Audio description is a means to inform individuals who are blind or who have low vision about visual content essential for comprehension. ... Audio description is usually added during existing pauses in dialogue. Audio description is also called video description and descriptive narration. https://www.acb.org/adp/ad.html
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❤ pants
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Number of posts: 22,632