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In reply to the discussion: Fuck Bill Maher....thought that needed a thread of it's own [View all]mr715
(2,068 posts)Are pretty bad. They are some associations with chronic use and neurodegeneration. They operate on the histamine system in the brain which is responsible for natural wakefulness and arousal. They also have immune effects that I'm not entirely up to date on.
By contrast, drugs like ambien operate on GABA, producing a much more natural "sleepiness" and they have a significantly shorter half-life in the body so they are less likely to produce hangovers. Plus, in my subjective experience, they are much more fun.
I've taken ambien for a long time. It has lost some of its efficacy, but when I started I could pop one right before bed and would wake up 7 hours later no alarm necessary like clockwork. Feeling great.
Plus, never impaired my debate performance.
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