93% of Americans have glyphosate in their bodies - UC Cal

[womanofthehills]

60. you are so so so wrong about Malathion - look up side effects of organophosphate pesticides

http://www.beyondpesticides.org/assets/media/documents/mosquito/documents/citizensHealthEffectsMosqP.pdf

Journal of Pesticide Reform
, Winter 1992, vol.12, no.9, p.29 (9).
This article examines the health effects of Malathion in human and
animal studies. Malathion is detrimental because it effects the
nervous system
by inhibiting the enzyme, acetylcholinesterase
(AchE), that breaks down acetylcholine, a chemical essential in
transmitting nerve impulses across junctions between nerves. Without functioning AchE,
acetylcholine accumulates to produce rapid twitching of voluntary muscles,
incoordination, convulsions, paralysis, and ultim
ately death. Acute toxicity reactions in
humans include headaches, nausea...blurred vision and pupil constriction, slowed
heartbeat, respiratory depression, paralysis, coma, as well as muscular damage (after
inhalation). Birth defects, reproductive problems, and genetic damage have been
associated with alathion exposure in humans and animals. Furthermore, Malathion has the
potential to contaminate ground and surface water. In California, five of twenty-eight
county water systems tested were contaminated with malathion¹ and storm drains in Santa
Clara County (where aerial sprays of malathion had been used for eradication programs)
concentrated Malathion and malaoxon, eventually draining into San Francisco Bay.² Drift
and aerial spray mosquito control programs can expose people to levels of Malathion that
can cause the aforementioned health effects.

http://www.atsdr.cdc.gov/MMG/MMG.asp?id=517&tid=92
Health Effects

Systemic malathion toxicity due to excess cholinergic stimulation may result from all routes of exposure. Symptoms include abdominal cramps, vomiting, diarrhea, pinpoint pupils and blurred vision, excessive sweating, salivation and lacrimation, wheezing, excessive tracheobronchial secretions, agitation, seizures, bradycardia or tachycardia, muscle twitching and weakness, and urinary and fecal incontinence. Seizures are much more common in children than in adults.
Death results from loss of consciousness, coma, excessive bronchial secretions, respiratory depression and cardiac irregularity.
Commercial malathion products often contain impurities and hydrocarbon solvents, such as xylene or toluene, which themselves can cause toxicity.
Toxicity of malathion depends on metabolic activation; thus, symptoms may appear from a few minutes to a few hours after exposure.

Respiratory

Malathion, like all organophosphate pesticides, inhibits acetylcholinesterase and alters cholinergic synaptic transmission at neuroeffector junctions (muscarinic effects), at skeletal myoneural junctions and autonomic ganglia (nicotinic effects), and in the central nervous system. Inhibition occurs when malaoxon, a metabolite of malathion, binds to acetylcholinesterase; thus, symptoms may be delayed after exposure. Signs and symptoms of poisoning vary according to age, dose, and concentration. Most systemic effects are secondary to inhibition of acetylcholinesterase.

Muscarinic effects include pinpoint pupils; blurred vision; hypersecretion by salivary, lacrimal, sweat, and bronchial glands; narrowing of the bronchi; nausea, vomiting, diarrhea, and crampy abdominal pains; urinary and fecal incontinence; and slow heart rate.

Nicotinic effects include muscle twitching, cramping, and weakness. Nicotinic stimulation can obscure certain muscarinic effects and produce rapid heart rate and high blood pressure.
CNS

CNS effects are often the earliest manifestations of poisoning in adults and constitute the major signs and symptoms in children. CNS effects include irritability, nervousness, giddiness, fatigue, lethargy, impairment of memory, confusion, slurred speech, visual disturbance, depression, impaired gait, convulsions, loss of consciousness, coma, and respiratory depression.
Peripheral Neurologic

Peripheral neurologic effects include muscle twitching and weakness due to inhibition of acetylcholinesterase at neuromuscular junctions.
Respiratory

Respiratory failure is the most common cause of death due to malathion poisoning. Narrowing of the bronchi and markedly increased bronchial secretions can occur. Respiratory failure results from respiratory depression coupled with paralysis of the respiratory muscles and progressive airway obstruction from bronchorrhea. In addition, pulmonary aspiration of the hydrocarbon solvents found in many commercial preparations can cause inflammation of the lungs.

Children may be more vulnerable because of relatively higher minute ventilation per kg and failure to evacuate an area promptly when exposed.
Cardiovascular

Most exposure victims experience bradycardia, but pulse rate may be increased initially and tachycardia is more common in very severe poisoning. Irregular heartbeat may occur.
Gastrointestinal

Nausea, vomiting, abdominal cramps, diarrhea, and fecal incontinence are common manifestations, regardless of the exposure route. These are generally the earliest symptoms to occur.
Dermal

Malathion is has been reported to cause skin irritation and sensitization. Because it is readily absorbed through the skin, skin contact can result in systemic poisoning.

Because of their relatively larger surface area:body weight ratio, children are more vulnerable to toxicants absorbed through the skin.
Ocular/Ophthalmic

Systemic poisoning typically causes pinpoint pupils and spasm of the muscle of visual accommodation (i.e., ciliary muscle) leading to blurred vision and aching pain in the eye. However, organophosphate poisoning may still be present without pinpoint pupils, and dilation of the pupils may even be noted occasionally. Eye irritation, if it occurs, is most likely caused by the hydrocarbon solvents used in commercial pesticide preparations.
Potential Sequelae

Complete recovery generally occurs within 10 days unless severe lack of oxygen has caused residual brain damage. CNS effects such as confusion, fatigue, irritability, nervousness, and impairment of memory can occasionally last for several weeks. There is no evidence that malathion induces delayed neurotoxicity.
Chronic Exposure

Persistent weakness and impaired memory have been reported to occur from low-level exposures to some organophosphates in the absence of acute cholinergic effects, but there is no reliable information on adverse health effects of chronic exposure to malathion.
Carcinogenicity

The International Agency for Research on Cancer has determined that malathion is unclassifiable as to its carcinogenicity to humans. In animals, malathion induced liver carcinogenicity at doses that were considered excessive.
Reproductive and Developmental Effects

Studies have been reported in which malathion induced transient testicular effects in rodents. Results from studies addressing reproductive or developmental effects in humans are inconclusive. Malathion is not included in Reproductive and Developmental Toxicants, a 1991 report published by the U.S. General Accounting Office (GAO) that lists 30 other chemicals of concern because of widely acknowledged reproductive and developmental consequences.
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