93% of Americans have glyphosate in their bodies - UC Cal

[Octafish]

105. EPA USED MONSANTO’S RESEARCH TO GIVE ROUNDUP A PASS

Sharon Lerner
The Intercept, Nov. 3 2015, 3:32 p.m.

EXCERPT...

But the EPA’s exoneration — which means that the agency will not require additional tests of the chemical’s effects on the hormonal system — is undercut by the fact that the decision was based almost entirely on pesticide industry studies. Only five independently funded studies were considered in the review of whether glyphosate interferes with the endocrine system. Twenty-seven out of 32 studies that looked at glyphosate’s effect on hormones and were cited in the June review — most of which are not publicly available and were obtained by The Intercept through a Freedom of Information Act request — were either conducted or funded by industry. Most of the studies were sponsored by Monsanto or an industry group called the Joint Glyphosate Task Force. One study was by Syngenta, which sells its own glyphosate-containing herbicide, Touchdown.

Findings of Harm Were Dismissed

Who pays for studies matters, according to The Intercept’s review of the evidence used in the EPA’s decision. Of the small minority of independently funded studies that the agency considered in determining whether the chemical poses a danger to the endocrine system, three of five found that it did. One, for instance, found that exposure to glyphosate-Roundup “may induce significant adverse effects on the reproductive system of male Wistar rats at puberty and during adulthood.” Another concluded that “low and environmentally relevant concentrations of glyphosate possessed estrogenic activity.” And a review of the literature turns up many more peer-reviewed studies finding glyphosate can interfere with hormones, affecting such things as hormonal activity in human liver cells, functioning of rat sperm, and the sex ratio of exposed tadpoles.

Yet, of the 27 industry studies, none concluded that glyphosate caused harm. Only one admitted that the pesticide might have had a role in causing the health problems observed in lab animals exposed to it. Some rats that consumed it were more likely to have to have soft stools, reduced body weight, and smaller litters. But because that evidence didn’t meet a test of statistical significance, the authors of the Monsanto study deemed it “equivocal.”

SNIP...

While recent research has shown that very low doses of endocrine disruptors can not only have health effects but effects that are more dramatic than those caused by higher doses, some of the studies dismiss clear examples of harm because they occur in animals given relatively low doses of the substance. A study prepared by Monsanto in 1990, for instance, noted a statistically significant increase in pancreatic cancers among rats exposed to a relatively low dose of Roundup. The rats had a 14 percent chance of cancer, compared to a 2 percent chance in the control group. But since some rats exposed to higher amounts of the chemical had lower cancer rates, the scientists concluded the elevation was “unrelated to glyphosate administration.”

A Flawed System

Independent scientists may come up with different results than industry-funded ones for a variety of reasons, including how a study is designed or carried out. But Michelle Boone, a biologist who served on an EPA panel that evaluated the safety of atrazine, another pesticide, told The Intercept that analysis of those results is an area particularly ripe for bias. “Once you have industry intimately involved in interpreting the data and how it’s written up, it’s problematic.”

Having companies fund and perform studies that affect them financially would seem to be an obvious conflict of interest, but that’s the standard practice at EPA. The glyphosate review, which was completed in June, was one of 52 reporting on the endocrine disrupting potential of pesticides, all of which relied heavily on industry-funded research and most of which concluded, as the one of glyphosate did, that there was no cause for further testing. (Though marketed as a weed killer, or herbicide, glyphosate is considered to be a pesticide by the EPA.)

CONTINUED...

https://theintercept.com/2015/11/03/epa-used-monsanto-funded-research/