Chronic low grade inflammation, LEF gives kudos to Trental, a generic drug that

[HysteryDiagnosis]

probably won't be in your doctors magic kit.


Chronic Inflammation
The Epidemic Disease of Aging
http://www.lef.org/LEFCMS/aspx/PrintVersionMagic.aspx?CmsID=32226

Numerous studies show that pentoxifylline (PTX) is a potent inhibitor of TNF-a, IL-1(b), IL-6 and other pro-inflammatory cytokines.<62-69> A similar number of studies show that DHA fish oil suppresses these same cytokines.<23-30, 31-32> In people suffering from a chronic disease involving elevated levels of the inflammatory cytokines, the daily administration of 400 mg to 800 mg of PTX and/or 1000 mg to 2000 mg of DHA fish oil could be of enormous benefit.

We have previously published information showing that cytokine-suppressing nutrients such as fish oil and nettle leaf prevent and treat a wide range of diseases. In the second addendum that appears at the end of this editorial, we review studies that substantiate the potential off-label benefits of PTX in protecting against inflammatory cytokine-induced diseases.

What You Should Do?

The number of inflammatory-related diseases that could be successfully treated with cytokine-lowering therapy is staggering. Pentoxifylline (PTX) is a cytokine-suppressing drug that has been overlooked by most of the medical establishment. Supplements such as fish oil, nettle leaf, DHEA and vitamin K possess mechanisms of suppressing inflammatory cytokines similar to PTX. There are no side-by-side comparisons that would enable us to categorically state whether PTX or natural agents (such as DHA fish oil) work better.

[Chemisse]

1. I just take a bit of aspirin each day.

I expect it's a whole lot cheaper, has been thoroughly tested and shown to be effective, and is regulated so that I can be sure of the potency and purity.

[HysteryDiagnosis]

3. Very good.... I noticed the 81mg "adult" dosages in the pharmacy, when I am hurting

from a long hard day at work I'll take two 325's. They work.

ON EDIT TO ADD:
This from a review of Trental.
http://www.rxlist.com/script/main/rxlist_view_comments.asp?drug=trental&questionid=fdb3696_pem

I have ringing in the ears. I was told by a doctor I had to live with this condition. I was not going to settle for this. I went and saw the best doctor in the country for my condition,and he gave me this drug to take. It has helped me so much and my ringing in my ears is almost gone. Always get a second opinion.I hope this helps helps someone.

[Mnemosyne]

4. My tinnitus is horrible, this is really working for you? Is it expensive? Thanks for info. n/t

[HysteryDiagnosis]

5. That is an independent review from this link below, I don 't take this drug, I would if I had to

for now I am sticking to DHA, Pycnogenol, Calmag, B-Complex, Milk Thistle, and Wild Yam.


http://www.rxlist.com/script/main/rxlist_view_comments.asp?drug=trental&questionid=fdb3696_pem

ON EDIT TO CORRECT: independant to independent

[Mnemosyne]

6. So is that combination helping? I am getting desperate it is so bad. n/t

[HysteryDiagnosis]

7. Read the Inflammation Syndrome, give it to your doc, Take Action. n/t

[TheWraith]

33. Just be alert for stomach or intestinal problems.

Aspirin isn't good for your stomach lining, and can cause bleeding, particularly in long-term doses.

[midnight]

2. K&R

[laconicsax]

8. Serious question: Does LEF pay you to post their marketing copy or are you doing it for free?

[BuddhaGirl]

9. there are no links to any of their products

This is excellent information, with lots of references.

It's really no big deal. There is one poster here who constantly posts links to the same anti- alternative medicine blog, do you think he/she is being paid to do that to boost its readership?

:shrug:

[HuckleB]

10. That's because he uses the print version for his posts here.

It's despicable and disingenuous. It's as if someone chose to post crap straight from Eli Lilly's web site. Oh, and selective references by a supplement seller are meaningless.

If you can't see that much, then, well, WOW! :wow:

[BuddhaGirl]

12. oh, ho hum

:wow:

[HuckleB]

13. That's right.

Keep pushing the unsupportable scams.

It's bizarre, at best.

:puke:

[BuddhaGirl]

15. What's bizarre is how exercised you get over

non-Big Pharma forms of medicine.

But hey, to each his own! :toast:

[HuckleB]

17. And the "Big Pharma" ad hominem strikes again!

:rofl:

I'm all for good medicine. I despise scams. Try again.

PS: http://www.democraticunderground.com/discuss/duboard.php?az=view_all&address=222x107489

[BuddhaGirl]

18. I'm all for good medicine too :-)

Plenty of ad hominems about alternative medicine fly around here so don't forget that!

:rofl:

[HuckleB]

19. No, you're not.

Evidence means nothing to you. If it did, then you could claim to be "all for good medicine too." Further, since most of the "alternative medicine" you push has not been shown to have any worth, what you refer to as ad hominem attacks may just be the reality of those scam treatments.

[BuddhaGirl]

20. Actually, yes I am and it's not for you to decide if evidence

"means nothing" to me.

But you believe what you choose to believe. And remember, it's your opinion if alternative medicine has no worth. :hi:

[laconicsax]

21. Does that mean that it's your opinion if real medicine has no worth?

I know you're replying to HuckleB, but I'm curious how evidence means anything to you when you reject it out of hand when it doesn't support your preexisting beliefs about CAM.

[HuckleB]

22. It's not about who decides. It's about the evidence that you make clear.

You repeatedly show that you don't care about evidence. I guess you think that pretending otherwise magically changes but, it really doesn't. Sorry.

[BuddhaGirl]

23. thinking that I don't care about evidence is YOUR magical thinking

and your projection. Sorry!

[HuckleB]

24. Nope.

You're posts are very clear on that issue. Whenever evidence goes against the magical thinking you prefer, you ignore it.

Again, pretending it isn't so, doesn't change a thing.

[BuddhaGirl]

27. "magical thinking" is a relative term

why don't you go back and find *all* my posts, and you'll see that what you believe isn't really true.

[HuckleB]

28. Show me one post by you that doesn't support your constant support of magical thinking.

Thanks.

[BuddhaGirl]

29. you keep accusing, the onus is on you

I really don't care what you believe about me, I just don't want you to get the last word :P

[HuckleB]

30. You've yet to post anything that conflicts with my impression of your world view.

So, until you do, all I have to do is point to the posts you've made. In fact, this response makes it very clear that the reality that you don't care about scientific evidence, the scientific process, etc..., and that you do little but root for "treatments" that you want to be worthy but have yet to be shown to be worthy. Until you do something different, your claims to care about evidence are just magic dust. To restate it: Your repeated, blind support for every anecdote offered to support "treatments" you want to believe is good evidence that you do what I'm claiming you do. How do you not see that?

[BuddhaGirl]

34. Your orientation and mine differ

thus, I really don't care what your "impression" of my "world view" is. I have stated before that I believe western/allopathic medicine has its place. So does alternative medicine, which is what I prefer.

If you call if "magic dust" that's your prerogative.

Suum cuique pulchrum est.

[HuckleB]

35. "Orientation?"

:rofl:

You don't like evidence. You like baseless belief. I like evidence. I don't like baseless belief.

Yes, those are two very different orientations. That is what I've been saying all along.

[BuddhaGirl]

38. yes, to each his own

I do like evidence too. There is a place for both allopathic and alternative medicine.

You reject alternative medicine, so we have different orientations.

The word has more than one meaning, so :rofl: back at you for your puerile interpretation!

[HuckleB]

39. I reject treatments that have no evidence base to support their use and their safety.

You have made it clear that you have no care for evidence, despite making a general claim. Your specific posts repeatedly make that claim false.

I could go into the rest of the logical fallacies you continue to offer, but I'm not feeling generous today.

It's quite a bizarre world you've created for yourself. "I care about evidence, uh, just as long as it isn't evidence I don't like." So, yeah :rofl: !!!!!!

[BuddhaGirl]

40. That's your perception

And your little world of "projection" is just as bizarre :rofl:

To each his own!

[laconicsax]

25. Methinks you don't understand what magical thinking means.

[BuddhaGirl]

26. methinks you don't know what projecting means

n/t

[laconicsax]

31. Nice comeback!

I hope you didn't stay up all night coming up with that one.

[BuddhaGirl]

37. most likely about as long as you did

:eyes:

[laconicsax]

11. Because the posts that had links were consistently locked and deleted.

For some reason, the mods feel that posting a for-profit company's marketing materials complete with medical advice is acceptable as long as the links to buy the products being advertised are hidden.

[HuckleB]

14. Well, alas, no one ever referred to DU as consistent.

[LaurenG]

16. Just an FYI if you take blood thinners vit K is a no-no.

Also, there are lots of foods that can aggravate inflammatory processes.

http://rheumatology.oxfordjournals.org/content/38/11/1039.full

[EvolveOrConvolve]

32. And of course LEF doesn't sell Trental, do they?

Do they?

[laconicsax]

36. Didn't you just post something denouncing evidence?

http://www.democraticunderground.com/discuss/duboard.php?az=view_all&address=222x108130

:shrug: