Interesting article.
Chronic fatigue syndrome, often dismissed as the imaginings of depressed and whiny people, is actually caused by genetic mutations that impair the central nervous system's ability to adapt to stressful situations, according to a major new study by the Centers for Disease Control and Prevention (CDC).
Small changes in many of the genes in the brain prevent the nervous system from rebounding from everyday stress and less frequent, stronger insults, eventually triggering a cascade of responses that leaves the patient severely debilitated, researchers reported Thursday in 14 separate papers in the journal Pharmacogenomics.
"This is the first credible evidence for a biological basis" for the syndrome, said CDC director Dr. Julie Gerberding.
The findings will provide immediate help in diagnosing the disorder, which often puzzles physicians because of the broad spectrum of symptoms and the absence of defining biochemical markers.
http://seattletimes.nwsource.com/html/nationworld/2002943726_fatigue21.html