Is it ok to comment in a church service? [View All]

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I've been to church perhaps 5 times in my life so I'm not very familiar with this. But for those who do know more about christianity - is it ok to question/comment on what the preacher says during the service?

Say you're listening to a rabid fundamentalist one or even one who isn't. If he says anyone who is gay is condemned to hell during his speech, or is essentially campaigning for a republican, can you stand up and ask questions or give a comment on what he said? Does it depend on which sect it is?

If not, why? And if not, what would happen if you did? Condemned to hell?

I know there are plenty of christians who don't agree with what the fundamentalists say so I'm wondering why they don't ever stand up and call them on it. Put them on the spot so to speak.