I got Punch-Out!! for the Wii today and it is AWESOME.

[Danger Mouse]

If you're a fan of the original for the NES (and who isn't??) you should pick it up. If only for the chance to pound on that hapless wuss Glass Joe one last time. I made it pretty far already (I think I'm near the end) but some of the opponents are brutal. Don't be expecting the same opponents you originally faced, though...everybody has been changed. A lot.
Also, the advice Doc gives you is hilarious, the opponents have as much personality as ever, and it's all in good (great!) fun.