http://www.foodconsumer.org/777/8/Weight_loss_may_up_death_risk.shtml Individuals who intended to lose weight and were successful had a higher mortality rate than those who planned to shed pounds but whose weight remained stable or went up. People who intended to lose weight and did so also had a higher mortality rate than those who did not aim to lose weight and kept their weight constant.
The authors suggested one possible explanation may be the unavoidable loss of lean body mass – which may outweigh the benefits of losing fat mass in healthy people.
The surprising results indicate a need for further study before the findings can “be used as basis for advice about intentional weight loss in the large population of otherwise healthy overweight and obese individuals.” The study also indicates the need to prevent the development of obesity altogether.
The study appeared in the June, 2005 issue of PLoS Medicine