caused by or related to the diabetic condition, excess glycation, and the oxidative stress caused by spikes in blood sugar levels.
Full abstract at link:
http://diabetes.diabetesjournals.org/cgi/content/abstract/db06-1003v2?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&fulltext=sulforaphane&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT>>Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease
OBJECTIVE–: Sulforaphane (SFN) is an activator of transcription factor NF-E2-related factor-2 (nrf2) that regulates gene expression through the promoter antioxidant response element (ARE). Nrf2 regulates the transcription of a battery of protective and metabolic enzymes. The aim of this study was to assess if activation of nrf2 by SFN in human microvascular endothelial cells prevents metabolic dysfunction in hyperglycemia.
CONCLUSION–: We conclude that activation of nrf2 may prevent biochemical dysfunction and related functional responses of endothelial cells induced by hyperglycemia in which increased expression of transketolase has a pivotal role.<<
Point is, sulforophane is in many organically grown, fully ripened flash freeze dried vegetable and fruit powders. Your local health science food store can hook you up if you do not have access to quality fully ripened veggies.