Coenzyme Q10 and Parkinson's Disease

[HysteryDiagnosis]

http://www.lef.org/protocols/prtcl-088b.shtml

In this study, cited in the October 2002 issue of Archives of Neurolgy, 80 Parkinson's patients consumed varying potencies of coenzyme Q10 or placebo for up to 16 months (Schults et al. 2002). When the study ended, the patients consuming the highest potency of CoQ10 showed a 44% reduction in the decline of motor skills, movement and mental function compared to the placebo group. Those receiving high-dose CoQ10 also demonstrated an improved ability to perform daily living tasks.

The dose required to induce this dramatic affect was 1200 mg a day, a far higher amount than had ever been administered to humans in the past. CoQ10 did not improve symptoms the way current Parkinson's drugs do. Instead, CoQ10 slowed the progression of the disease, something that Parkinson's drugs don't do.

Independent analysts stated that these results were "tremendously encouraging," but cautioned that more studies should be done to confirm these effects. While Life Extension encourages more studies, it would appear that those with Parkinson's disease should consider supplementing with 1200 mg of CoQ10 a day.

In a 2003 report published in Neuroscience Letters (Muller et al.), 360 mg per day of CoQ10 were administered to Parkinson’s patients for 4 weeks. The researchers noted mild symptomatic improvement compared to placebo. More importantly, an established clinical test to measure Parkinson’s symptom function showed significantly better improvement of performance in the CoQ10-supplemented patients compared to placebo.

[medeak]

1. husband has been on high dose

since being diagnosed 3 years ago.

His doctor sent me this...and made me laugh as he poo pooed me putting him on it initially.

[Celebration]

2. Hope they do some more studies, and also on NADH

NADH is another coenzyme that may be beneficial for Parkinson's Disease. I am linking this as being a preliminary type study, not as definitive proof or anything like that.

http://www.nadh.com/parknson/Prkns105.htm

[The Straight Story]

3. Thanks for the info, wife was just diagnosed with parkinson's

She is greatly upset and I will be sure to pass this along to her. Thanks for posting!!

[HysteryDiagnosis]

4. You may want to read the entire article.... and then perhaps

google for glyconutrients as well....

AND read this book if you can.

http://ec1.images-amazon.com/images/P/0929173252.01._BO2,204,203,200_PIsitb-dp-500-arrow,TopRight,45,-64_AA240_SH20_SCLZZZZZZZ_.jpg

http://www.amazon.com/gp/product/0929173252/sr=8-1/qid=1147343192/ref=pd_bbs_1/104-7479541-9947118?%5Fencoding=UTF8

Reviewer: A reader
I would like to thank the reviewers who gave a favorable review, but especially I would like to say to those who were helped by the book, God bless you. As for the harshly critical reviewers, most are from those who know little about the subject and could care less. At least one prefers hedonistic pleasures of gustatory stimulation over scientific fact and logical conclusions based on science. I direct this at the reviewer who stated, rather condescendingly, that I knew very little biochemistry and was so uninformed that I wasn't aware that Parkinson's disease occurred before the arrival of MSG and aspartame. In fact I majored in biochemistry in undergraduate school and completed with honors biochemistry in medical school. I continue to be a student of neurochemistry. My articles on these subjects are printed in peer-reviewed medical journals, which I'm sure the reveiwer would have difficulty understanding. Cysteine is a neurotoxin, as is homocysteine, phenalanine, glutamate and aspartate and a number of naturally occurring amino acids. Has the reviewer ever heard of PKU?

While cysteine plays a vital role in brain protection, it is only safe as the N-acetyl product and as cystine. Cysteine, beside being an excitotoxin itself, is converted to homocysteic and homocysteine sulphinic acid, both very powerful excitotoxins. Sulfite, a metabolite of cysteine, is also a powerful neurotoxin (as in sulfate oxidase deficiency). As for the causation of Parkinson's and other neurodegenrative diseases, I never said they were exclusively caused by food born excitotoxins-in fact, in three places in the book I make this point. I do contend they exacerbate the symptoms and accelerate the progression of these diseases. An abundance of new evidence confirms what I wrote in the book and, in fact, paints an even more ominous picture. I cover some of this new information in my recently released book, Health and Nutrition Secrets. As far as making tons on money on my book sales-that is a dream in the head of my angry and confused critic. I don't mind criticism that is logical and based on careful study. These critics are not qualified and did not read the book critically and carefully. The proof of my thesis that food borne excitotoxins are dangerous to human health continues to arrive in the scientific literature.