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As a retired nurse I normally look to medical literature and not attorneys for my medical info. But as I am not feeling well today due to a flare of my MS here is what my first link says. Yea I know it is US news and world report but it is my first hit and I am not up to a lot of real research.
Lane said there are several theories as to how alendronate could be related to these fractures. One is that the drug slows down the development of new collagen, and he said new collagen is very strong. Another could be because there is slower bone turnover on the medications. That could mean there may be accumulated microdamage in the bone, making it more susceptible to fracture in certain women.
Lane said that women taking this medication should keep taking it, and these findings shouldn't cause them alarm. "This is a great drug that does wonderful things. Bisphosphonates have dropped the rate of hip fractures," he added.
Ron Rogers, a spokesman for Merck, which manufactures Fosamax, said, "Fosamax has not been associated with an increased risk of fracture at any skeletal site." Rogers also noted that this study didn't prove a cause and effect relationship between the drug and these unusual fractures, and that the researchers noted that 63 percent of women treated for low-energy fractures weren't taking bisphosphonates at all. (of course this is merck talking :eyes: :puke: )
Dr. Loren Wissner Greene, co-director of the osteoporosis and metabolic bone disease program at the New York University School of Medicine, agreed that this study has just pointed out an association between Fosamax use and these fractures, not proven a causal relationship.
Still, Greene said she believes these atypical breaks probably are related to the medication, although she added, "If this is a related complication, it appears to be very rare." Like Lane, she said, "Alendronate is still a very valuable drug in decreasing the risk of hip fracture." But, she said, what would be helpful is a test that could identify who is in the sub-population that might have a problem on this medication.
ON the other hand my husband who is a family physician no longer uses it as he does not think it is worth the risk. He uses other drugs for the problem. Still it seems if one is doing a show on the problems with the drug that they would have a medical expert on to talk about the risks and possible side effects.
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