Kill Bill was a funny movie but when it comes to the real world,

[HysteryDiagnosis]

the best medicine money can buy will no doubt NEVER consider the following. A former president SHOULD BE made aware of the information that follows.


Heart Fail Rev. 2006 Mar;11(1):75-82.
The management of conditioned nutritional requirements in heart failure.

Allard ML, Jeejeebhoy KN, Sole MJ.

Division of Cardiology, University Health Network, Toronto, Ontario.

Patients suffering from congestive heart failure exhibit impaired myocardial energy production, myocyte calcium overload and increased oxidative stress. Nutritional factors known to be important for myocardial energy production, calcium homeostasis and the reduction of oxidative stress, such as thiamine, riboflavin, pyridoxine, L-carnitine, coenzyme Q10, creatine and taurine are reduced in this patient population. Furthermore, deficiencies of taurine, carnitine, and thiamine are established primary causes of dilated cardiomyopathy. Studies in animals and limited trials in humans have shown that dietary replacement of some of these compounds in heart failure can significantly restore depleted levels and may result in improvement in myocardial structure and function as well as exercise capacity. Larger scale studies examining micronutrient depletion in heart failure patients, and the benefits of dietary replacement need to be performed. At the present time, it is our belief that these conditioned nutritional requirements, if unsatisfied, contribute to myocyte dysfunction and loss; thus, restoration of nutritional deficiencies should be part of the overall therapeutic strategy for patients with congestive heart failure.

PMID: 16819580

Altern Ther Health Med. 2009 Mar-Apr;15(2):48-50.
Metabolic cardiology: the missing link in cardiovascular disease.

Sinatra ST.

University of Connecticut School of Medicine in Farmington, USA.

The importance of supporting energy production in heart cells and the preservation of the mitochondria in these cells will be the focus of a new frontier in cardiovascular prevention, treatment, and management. Many physicians are not trained to look at heart disease in terms of cellular biochemistry; therefore, the challenge in any metabolic cardiology discussion is in taking the conversation from the "bench to the bedside." An understanding of the vital role that adenosine triphosphate (ATP) plays in the heart is critical for any physician or clinician considering therapeutic options that support ATP production and turnover in jeopardized cardiac muscle cells. Metabolic therapies that help cardiomyocytes meet their absolute need for ATP fulfill a major clinical challenge of preserving pulsatile cardiac function while maintaining cell and tissue viability. D-ribose, L-carnitine, and coenzyme Q10 work in synergy to help the ischemic or hypoxic heart preserve its energy charge. This article introduces how ATP, diastolic heart function, and metabolic support help maintain cardiac energy by preserving ATP substrates. Part 2 will investigate an in-depth biochemical discussion of congestive heart failure with physiologic, pathophysiologic, and treatment considerations.

PMID: 19284182


Altern Ther Health Med. 2009 May-Jun;15(3):44-52.
Metabolic cardiology: an integrative strategy in the treatment of congestive heart failure.

Sinatra ST.

University of Connecticut School of Medicine, Farmington, USA.

Congestive heart failure (CHF) and dilated cardiomyopathy are life-threatening conditions in which the heart muscle is so weak that effective pulsatile action is compromised. Pulmonary vascular congestion and swelling in the lower extremities as well as in the liver and lining of the gastrointestinal tract frequently cause overwhelming symptoms and disability. Millions of Americans suffer from CHF, and more than 500,000 cases are diagnosed annually. Cardiovascular diseases such as hypertension with left ventricular hypertrophy, valvular heart disease, coronary artery disease, myocarditis, and various cardiomyopathies can lead to the progressive onset of CHF. The purpose of this communication article is to introduce metabolic cardiology as a vital therapeutic strategy utilizing nutritional biochemical interventions that preserve and promote adenosine triphosphate (ATP) production. Treatment options that incorporate metabolic interventions targeted to preserve energy substrates (D-ribose) or accelerate ATP turnover (L-carnitine and coenzyme Q10) are indicated for at-risk populations or patients at any stage of CHF. The integration of these metabolic supports provides the missing link in CHF treatment that has been eluding physicians for decades.

PMID: 19472864

[NYC_SKP]

1. I learned this morning that more often than not stents are put in unnecessarily...

...and without the recommended stress test that would tell surgeons where the blockage is.

And expensive and unnecessary procedure driving up the cost of care.

It was a seminar on high health care costs...

[HysteryDiagnosis]

2. It is ridiculous to think that a supplementation program targeting

the heart with key nutrients could eliminate this sort of problem, the plaque buildup etc.

[The Magistrate]

3. Different Conditions, Sir

Congestive heart failure is a seperate item from arteriosclerosis.

[HysteryDiagnosis]

4. Congestive heart failure is a seperate item from arteriosclerosis.

# Arteriolosclerosis is any hardening (and loss of elasticity) of large arteries and arterioles (small arteries). It is often due to hypertension.

# Atherosclerosis is a hardening of an artery specifically due to an atheromatous plaque. Atherosclerosis is the most common form of arteriosclerosis.

How much would you wager that Bill Clinton is getting Coenzyme Q10 from the best medical minds money can buy?? I'll bet he's on statins only bigger than spit. Statins with Coenzyme Q10 may in fact be better for a person than either alone.



Role of coenzyme Q10 (CoQ10) in cardiac disease, hypertension and Meniere-like syndrome.

Kumar A, Kaur H, Devi P, Mohan V.

Cardiology Deptt, Govt. Medical College/GND Hospital, Amritsar, Punjab, Amritsar, Punjab, India. [e-mail]

Coenzyme Q10 (ubiquinone) is a mitochondrial coenzyme which is essential for the production of ATP. Being at the core of cellular energy processes it assumes importance in cells with high energy requirements like the cardiac cells which are extremely sensitive to CoQ10 deficiency produced by cardiac diseases. CoQ10 has thus a potential role for prevention and treatment of heart ailments by improving cellular bioenergetics. In addition it has an antioxidant, a free radical scavenging and a vasodilator effect which may be helpful in these conditions. It inhibits LDL oxidation and thus the progression of atherosclerosis. It decreases proinflammatory cytokines and decreases blood viscosity which is helpful in patients of heart failure and coronary artery disease. '

It also improves ischemia and reperfusion injury of coronary revascularisation. Significant improvement has been observed in clinical and hemodynamic parameters and in exercise tolerance in patients given adjunctive CoQ10 in doses from 60 to 200 mg daily in the various trials conducted in patients of heart failure, hypertension, ischemic heart disease and other cardiac illnesses. Recently it has been found to be an independent predictor of mortality in congestive heart failure. It has also been found to be helpful in vertigo and Meniere-like syndrome by improving the immune system. Further research is going on to establish firmly its role in the therapy of cardiovascular diseases.

PMID: 19638284