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Godhumor Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Feb-28-11 12:32 PM
Original message
An Alzheimer's vaccine in a nasal spray
http://scienceblog.com/43174/an-alzheimers-vaccine-in-a-nasal-spray/

By BJS (Science Blog)

One in eight Americans will fall prey to Alzheimer’s disease at some point in their life, current statistics say. Because Alzheimer’s is associated with vascular damage in the brain, many of them will succumb through a painful and potentially fatal stroke.

But researchers led by Dr. Dan Frenkel of Tel Aviv University’s Department of Neurobiology at the George S. Wise Faculty of Life Sciences are working on a nasally-delivered 2-in-1 vaccine that promises to protect against both Alzheimer’s and stroke. The new vaccine repairs vascular damage in the brain by rounding up “troops” from the body’s own immune system.

And in addition to its prophylactic effect, it can work even when Alzheimer’s symptoms are already present. The research on this new technology was recently accepted for publication in the journal Neurobiology of Aging.

...

Could the breakthrough lead to both a vaccine and a long-sought cure for Alzheimer’s disease? “It appears that this could be the case,” says Dr. Frenkel, who worked on the study with his doctoral student Veronica Lifshitz and master degree students Ronen Weiss and Tali Benromano. “We’ve found a way to use the immune response stimulated by this drug to prevent hemorrhagic strokes which lead to permanent brain damage,” he says.
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More and more Alzheimer's research is being done, and it seems like we keep getting a little closer to solving the issue once and for all. Here's hoping this is another step towards that final goal.

By the way, Science Blog is excellent for those of you who've never been there.
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mainer Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Feb-28-11 12:44 PM
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1. Unfortunately, a long way from controlling amyloid to reversal of symptoms
It's not even clear that amyloid is the causative culprit. This spray may be able to control amyloid, but will it cure Alzheimer's?

Would like to see more on this soon.
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Godhumor Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Feb-28-11 12:48 PM
Response to Reply #1
3. Agree completely, it will be interesting to see the response when it is journal published
As people start punching holes in it, hopefully there will still be a strong base to build on.
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kickysnana Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Feb-28-11 03:58 PM
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6. +1
Dead end vaccine.
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Exultant Democracy Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Feb-28-11 12:46 PM
Response to Original message
2. k%r
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arikara Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Feb-28-11 12:52 PM
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4. I dont believe it for a minute
how can they have a vaccine when they don't even know what causes it. And a vaccine is not going to prevent a stroke either. They are going to have peoples immune system so constantly artificially stimulated by all these witches brews that will be causing more health problems too.
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Godhumor Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Feb-28-11 12:57 PM
Response to Reply #4
5. It has just been accepted for journal review and has yet to enter human testing
It still has many, many steps to go before it gets to that point. What it looks like, based on this early stage, is that it breaks down and prevents the plaque build-up on the brain nerves, which would significantly lessen the damage caused by Alzheimer's

"Witches Brew" would be if it didn't go through any of this testing, was called something like "Nature's Cure" and sold next to holistic treatment kits. This won't go through those steps.
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