First three paragraphs due to rules. I guess you can take your pick.
http://www.bccancer.bc.ca/PPI/UnconventionalTherapies/VitaminETocopherol.htm"The toxicity of vitamin E in adults appears to be low. Clinical trials have shown that large doses (e.g., 200-800 mg/d) do not result in serious side effects in most adults, with the possible exception of individuals taking oral anticoagulant therapy and those with vitamin K-related clotting disorders. High levels of vitamin E can adversely affect the absorption of vitamins A and K, and long-term use of high doses may cause nausea, diarrhea and blurred vision. High-dose therapy in infants may be associated with more serious side effects." (Kaegi)
"Megadose of vitamin E may depress blood coagulation. Platelet aggregation is inhibited and the prothrombin time may be prolonged." (Loescher) (Ontario)
According to one study, alpha-tocopherol increased the risk of coronary heart disease. "Based on these findings, we recommend that patients with a previous myocardial infarction who smoke should not use this agent." (Rapola)
http://www.nlm.nih.gov/medlineplus/ency/article/002406.htmSide Effects
There is no known dietary deficiency of vitamin E.
There are no known toxic effects to megadoses of vitamin E. Occasional side effects such as headache have been reported.