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Tumor cells use protein recycling to speed growth (BBC)

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eppur_se_muova Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Nov-17-11 03:34 PM
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Tumor cells use protein recycling to speed growth (BBC)
Tumours ramp up recycling efforts

By James Gallagher
Health reporter, BBC News

Protein recycling in the body could be a critical part of tumour formation, researchers believe.

A report in Science Translational Medicine showed that protein recycling was accelerated in more than 30 types of cancerous cell.

When scientists interrupted the process in mice with cancer, the tumours began to shrink.

The results were described as "exciting" and as a new target for drug development.

The recycling process studied was "chaperone-mediated autophagy" (CAM) {uh, that's CMA}. It is a normal part of a cell's routine, removing damaged goods and recycling the raw materials.
***
more: http://www.bbc.co.uk/news/health-15756731





A promising development, with the usual caveat that any successful treatment will still be years down the road.


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supernova Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Nov-17-11 05:33 PM
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1. My 2 cents
Any way they can interrupt a tumor cell's aggressive growth: interrupted blood supply, intuerrupted protein recycling, is bound to be less toxic to the rest of the body than the standard of care we have now.
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